THINGS YOU HAVE CONTROL OVER
1. You're using the memoir format to make a political or domestic point.
I'm not interested in being lectured to in any form, and particularly not in 300+ pages.
A good memoir is so brutally honest that it's painful. That means you're exploring yourself, not pointing fingers at someone else.
2. Your premise and plot are utterly derivative.
If your book sounds like a 70's TV cop show, it's a pass. The world has moved on from Cagney and Lacey, and even Starsky and Hutch.
If your book sounds like something Michael Connelly wrote, it's a pass. I've read his books, and liked them. I'm not looking for you to reprise it.
3. Your query contains the words "it's a must read."
That's marketing hyperbole. It's not the plot, it's not even a description of the book. If you don't understand that now, I don't want to take on the task of teaching you.
4. Misused/wrong words
I've steeled myself to overlook your almost universal inability to properly conjugate the verb to lie.
I've shut my eyes to consistent its/it's errors.
But honestly, words are your tools. When you get them wrong, it's just painful.
I love words.
Watching you torture them is something no agent wants to see.
THINGS YOU DO NOT HAVE CONTROL OVER
1. The market for this kind of book is contracting not expanding.
It will take me more time and effort to find a home for this than I'll reap in commissions.
2. It's not a book I like.
That doesn't mean anything other than you think I have bad taste.
There are quite a few published books that I think are rubbish. And they're doing quite well.
You just need a different agent.
3. I tried to sell a similar book and couldn't.
I try not to do that same thing again.