My godsend Meredith takes first crack at the queries. She's able to promptly reply to all the people whose work is really not right for us. I've posted query stats before; she takes care of the ones where there's no mention of what the book is about; topics I don't ever want to see; people who really aren't ready to query. She knows what I'm looking for, and more important, what I'm NOT looking for at all.
The balance of the queries are things she reads more carefully, and talks to me about. I sit directly across from her and we have conversations about queries almost every day.
Now, if I didn't have Meredith the Godsend (and trust me, that is not a thing I like to contemplate) your work would get LESS careful scrutiny not more.
What does this mean to you: never EVER think that having an assistant read your query is somehow a bad thing. Without Meredith I'd be hard pressed to answer all my queries promptly; without her I wouldn't have read some things she's brought to my attention; and without her I'd have to close to queries much more often.
If you're smart, you'll realize the godsends are just that.