Knowing how hard it is to craft an effective query, is it advisable to slant or bias a query based on the gender of an agent? Ultimately, it is the story that sells, but when I read in an agent's preference list, "Give me a strong female protagonist." I think my male oriented query might as well pound salt. It seems to me that some agent/gatekeepers have shut the door and encrypted the lock.
I asked my staff, all two of them and both women, what they look for in a book. They said, hot guy(s), plenty of steam and a choice by the female protagonist between two or more male, love interests. Of course, none of which fits my story. Keeping their advice in mind, I wrote a separate query using Meri, a character with a large POV footprint, and a love interest that can be construed as a triangle--without being dishonest. But it is disingenuous, because I don't see Meri as the protagonist. So, other than outright lying, is everything fair in love and querying to get an agent to read pages?
Your staff are describing books that would be shelved in the romance or womens' fiction category. Your novel isn't either of those (I know this cause I'm reading about it over at QueryShark.) They're the wrong focus group for you to consult.
There's nothing wrong with tailoring a query to an agent's interest. Tailoring it to the agent's gender is a recipe for disaster. For starters, us girls have widely varying tastes. For example, I've heard that LaSlitherina prefers her protagonists drink vodka. And Polish vodka at that. Or was it potato vodka? I, on the other hand, prefer they drink the blood of ....well, never mind about that now.
Then of course the troublesome case of Brooks Sherman. My trusty cohort in crime has been addressed on more than one occasion as Ms. We think it's hysterical. He. Does. Not. Unless you know the gender of the agent, some of those names can confuse you: Flip. Binky. Cameron.
What you're doing is the new wrinkle on the old art of Kremlinology: trying to intuit reasons for things based on what you can observe. You must remember that much of what goes on here in the Query Corral is not visible. (Nor should it be--see cliche about making sausage)
I look for good stories that I want to read. There are many good stories I don't want to read. And sometimes, I want to read things that I thought were good and turn out to be ...well.. not.
Keep writing. Keep revising. Quit fulminating about gatekeepers. We're not. We're your first step on the road to success, and we're looking for you every single day.